This is the perfect pen for drawing eyelashes, fine lines, intricate details, and writing. Does not run, smudge, or bleed. Water based. Al. They are non-toxic and should be considered for decoration use only. Non-toxic means it isn't toxic if ingested and the ingredients are not absorbed by your body.This combination pack includes 1 The Ultra Fine tip is amazing for highlighlighting and designing very fine details and fonts. (drys instantly). The tweets Pens are smudge and bleed proof and will resist any extract, vodka or Everclear when mixing with gel food colors, Luster, Petal, Matte and Metalic dust powders. Painting with water is not recomended. Pens are designed to be used on dry Royal Icing, Dry Fondant, Wafer Paper, FlexFrost Fabric, and Gumpaste.